Inclusion Criteria

Clinical features

  1. Frequent typical absence seizures (several to many per day)
  2. Age of onset between 3-9 years
  3. No prior history of epileptic seizures (except febrile convulsions)
  4. With or without generalized tonic clonic seizures
  5. No partial tonic/clonic seizures
  6. Normal child development
  7. Normal intelligence and normal neurological exam
  8. No signs of CNS inflammation, trauma or metabolic disease

EEG

  1. At least one EEG with bilateral and synchronous 3Hz spike and wave on normal background activity
  2. No interictal diffusely slow background activity
  3. No generalized spike and waves slower than 2.5 Hz
  4. No focal or multi focal spikes, especially activated during sleep or brief runs of generalized rapid spikes

Response to anti epileptic medication

  1. Immediate response to anti-epileptic medication
  2. Good seizure control under AE's

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